Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.E490K
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KIT

NM_000222.3:p.E490K

Associated Papers

Comparative analysis of RNA expression in a single institution cohort of pediatric cancer patients.

Vasquez YA et al.

Npj Precision Oncology, 2025

40119139 (PubMed )
Supplement: 41698_2025_852_MOESM11_ESM.xlsx › Supplementary_Data_9

Molecular and Functional Key Features and Oncogenic Drivers in Thymic Carcinomas.

Barachini S et al.

Cancers, 2023

Plasma Sequencing for Patients with GIST-Limitations and Opportunities in an Academic Setting.

Falkenhorst J et al.

Cancers, 2022

36428589 (PubMed )
Supplement: cancers-14-05496-s001.zip › cancers-1969013-supplementary.pdf

Targeted Next-Generation Sequencing of Thymic Epithelial Tumours Revealed Pathogenic Variants in KIT, ERBB2, KRAS, and TP53 in 30% of Thymic Carcinomas.

Szpechcinski A et al.

Cancers, 2022

35884448 (PubMed )
Supplement: cancers-14-03388-s001.zip › Szpechcinski_Szolkowska_-_NGS_analysis_of_53_thymic_epithelial_tumors_-_Table_S3.pdf

Mutation analysis of the EGFR gene and its downstream signaling pathway in thymic carcinoma patients from a Chinese Han population.

Zhan P et al.

The Clinical Respiratory Journal, 2018

Stabilization of disease after targeted therapy in a thymic carcinoma with KIT mutation detected by clinical next-generation sequencing.

Hagemann IS et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2014

When a thymic carcinoma "becomes" a GIST.

Rossi V et al.

Lung Cancer (amsterdam, Netherlands), 2013

Activating c-KIT mutations in a subset of thymic carcinoma and response to different c-KIT inhibitors.

Schirosi L et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2012

Reappraisal of KIT mutation in adenoid cystic carcinomas of the salivary gland.

Sung JY et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."