Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.F506delins
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KIT

NM_000222.3:p.F506delins

Associated Papers

Imatinib elicited a favorable response in a dog with a mast cell tumor carrying a c-kit c.1523A>T mutation via suppression of constitutive KIT activation.

Yamada O et al.

Veterinary Immunology and Immunopathology, 2011

Mutations in the fifth immunoglobulin-like domain of kit are common and potentially sensitive to imatinib mesylate in feline mast cell tumours.

Isotani M et al.

British Journal of Haematology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."