Associated Papers
CRISPR/Cas9-engineering of HMC-1.2 cells renders a human mast cell line with a single D816V-KIT mutation: An improved preclinical model for research on mastocytosis.
Bandara G et al.
Frontiers in Immunology, 2023
XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation.
Sun J et al.
Oncogenesis, 2018
KIT-D816V oncogenic activity is controlled by the juxtamembrane docking site Y568-Y570.
Chaix A et al.
Oncogene, 2014
Src-like-adaptor protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling.
Kazi JU et al.
Journal of Cell Science, 2014
Molecular alterations of KIT and PDGFRA in GISTs: evaluation of a Portuguese series.
Gomes AL et al.
Journal of Clinical Pathology, 2008
Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.
Masson K et al.
The Biochemical Journal, 2006
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction.
Lennartsson J et al.
Oncogene, 1999
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