Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.D572Y
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KIT

NM_000222.3:p.D572Y

Associated Papers

Identification of novel pathogenic roles of BLZF1/ATF6 in tumorigenesis of gastrointestinal stromal tumor showing Golgi-localized mutant KIT.

Kwon Y et al.

Cell Death and Differentiation, 2023

37704840 (PubMed )
Supplement: 41418_2023_1220_MOESM1_ESM.pdf

Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors.

Kim WK et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

27440273 (PubMed )
Supplement: 10780432ccr160521-sup-162954_1_supp_3538093_z8p3zw.pdf

Secondary mutations of c-KIT contribute to acquired resistance to imatinib and decrease efficacy of sunitinib in Chinese patients with gastrointestinal stromal tumors.

Gao J et al.

Medical Oncology (northwood, London, England), 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."