Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.H697Y
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KIT

NM_000222.3:p.H697Y

Associated Papers

Comparative analysis of RNA expression in a single institution cohort of pediatric cancer patients.

Vasquez YA et al.

Npj Precision Oncology, 2025

40119139 (PubMed )
Supplement: 41698_2025_852_MOESM11_ESM.xlsx › Supplementary_Data_9

Molecular and Functional Key Features and Oncogenic Drivers in Thymic Carcinomas.

Barachini S et al.

Cancers, 2023

The clinical utility and costs of whole-genome sequencing to detect cancer susceptibility variants-a multi-site prospective cohort study.

Davidson AL et al.

Genome Medicine, 2023

37723522 (PubMed )
Supplement: 13073_2023_1223_MOESM1_ESM.xlsx › Table_S4

Unraveling molecular networks in thymic epithelial tumors: deciphering the unique signatures.

Zhang X et al.

Frontiers in Immunology, 2023

Targeted Next-Generation Sequencing of Thymic Epithelial Tumours Revealed Pathogenic Variants in KIT, ERBB2, KRAS, and TP53 in 30% of Thymic Carcinomas.

Szpechcinski A et al.

Cancers, 2022

35884448 (PubMed )
Supplement: cancers-14-03388-s001.zip › Szpechcinski_Szolkowska_-_NGS_analysis_of_53_thymic_epithelial_tumors_-_Table_S3.pdf

Characterization of the Genomic Landscape in Cervical Cancer by Next Generation Sequencing.

Qiu L et al.

Genes, 2022

35205332 (PubMed )
Supplement: genes-13-00287-s001.zip › genes-1527502-supplementary.pdf

Genomic profiling reveals high frequency of DNA repair genetic aberrations in gallbladder cancer.

Abdel-Wahab R et al.

Scientific Reports, 2020

33328484 (PubMed )
Supplement: 41598_2020_77939_MOESM1_ESM.xlsx › Sheet1

C-KIT mutation in thymic carcinomas.

Terzi N et al.

Polish Journal of Pathology : Official Journal of the Polish Society of Pathologists, 2020

Development and validation of a targeted gene sequencing panel for application to disparate cancers.

McCabe MJ et al.

Scientific Reports, 2019

31745186 (PubMed )
Supplement: 41598_2019_52000_MOESM2_ESM.xlsx › Sheet1

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Brown AL et al.

Plos Computational Biology, 2019

31034466 (PubMed )
Supplement: pcbi.1006981.s010.xlsx › final_benchmark

Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Deng Q et al.

Heliyon, 2018

30603682 (PubMed )
Supplement: mmc2.xlsx › Raw_reads_info

Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers.

Heim D et al.

Genome Medicine, 2018

30442178 (PubMed )
Supplement: 13073_2018_591_MOESM4_ESM.xlsx › Table_S2

Integrative omics analyses broaden treatment targets in human cancer.

Sengupta S et al.

Genome Medicine, 2018

30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 3

Stabilization of disease after targeted therapy in a thymic carcinoma with KIT mutation detected by clinical next-generation sequencing.

Hagemann IS et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2014

Thymoma versus thymic carcinoma: differences in biology impacting treatment.

Kelly RJ

Journal of the National Comprehensive Cancer Network : Jnccn, 2013

Activating c-KIT mutations in a subset of thymic carcinoma and response to different c-KIT inhibitors.

Schirosi L et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2012

Absence of gene mutations in KIT-positive carcinoma showing thymus-like elements of the thyroid.

Pan Y et al.

Human Pathology, 2012

Imatinib mesylate in thymic epithelial malignancies.

Palmieri G et al.

Cancer Chemotherapy and Pharmacology, 2012

Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.

Girard N et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."