Varaico: Literature-Extracted Genetic Variants

Gene:KIT
Variant:p.D792E
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KIT

NM_000222.3:p.D792E

Associated Papers

The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.

Agarwal S et al.

Oncogene, 2015

Hotspot mutations in KIT receptor differentially modulate its allosterically coupled conformational dynamics: impact on activation and drug sensitivity.

Chauvot de Beauchêne I et al.

Plos Computational Biology, 2014

Allosteric communication across the native and mutated KIT receptor tyrosine kinase.

Laine E et al.

Plos Computational Biology, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."