Associated Papers
Warburg-Cinotti disease variant p.Tyr740Cys enhances catalytic activity of DDR2 kinase.
Hao Z et al.
Plos One, 2025
Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.
Kazi JU et al.
Cellular and Molecular Life Sciences : Cmls, 2017
Protein Tyrosine Phosphatase PRL2 Mediates Notch and Kit Signals in Early T Cell Progenitors.
Kobayashi M et al.
Stem Cells (dayton, Ohio), 2017
Molecular Analysis of Gene Rearrangements and Mutations in Acute Leukemias and Myeloid Neoplasms.
Sholl LM et al.
Current Protocols in Human Genetics, 2017
The activation loop tyrosine 823 is essential for the transforming capacity of the c-Kit oncogenic mutant D816V.
Agarwal S et al.
Oncogene, 2015
A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis.
Balci TB et al.
British Journal of Haematology, 2014
Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.
Agarwal S et al.
The Journal of Biological Chemistry, 2013
Allosteric communication across the native and mutated KIT receptor tyrosine kinase.
Laine E et al.
Plos Computational Biology, 2012
Molecular analysis of gene rearrangements and mutations in acute leukemias and myeloproliferative neoplasms.
Sholl LM et al.
Current Protocols in Human Genetics, 2010
Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance.
DiNitto JP et al.
Journal of Biochemistry, 2010
Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms.
Grimwade LF et al.
British Journal of Haematology, 2009
Allele-specific polymerase chain reaction for the imatinib-resistant KIT D816V and D816F mutations in mastocytosis and acute myelogenous leukemia.
Corless CL et al.
The Journal of Molecular Diagnostics : Jmd, 2006
A case of smouldering mastocytosis with peripheral blood eosinophilia and lymphadenopathy.
Hauswirth AW et al.
Leukemia Research, 2002
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