Varaico: Literature-Extracted Genetic Variants

Gene:KLF11
Variant:p.Q62R
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KLF11

NM_003597.5:p.Q62R

Associated Papers

Novel Kruppel-like factor 11 variant of maturity-onset diabetes of the young type 7: A case report.

Alvarez M et al.

World Journal of Diabetes, 2025

Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson's Disease.

Grigor'eva EV et al.

International Journal of Molecular Sciences, 2023

36901867 (PubMed )
Supplement: ijms-24-04437-s001.zip › ijms-2163006-supplementary.pdf

Genetic and Functional Analyses of the Novel KLF11 Pro193Thr Variant in a Three-Generation Family with MODY7.

Guan G et al.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 2023

Maturity-Onset Diabetes of the Young: Mutations, Physiological Consequences, and Treatment Options.

Younis H et al.

Journal of Personalized Medicine, 2022

A novel KLF11 variant in a family with maturity-onset diabetes of the young.

Wu S et al.

Pediatric Diabetes, 2022

Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY.

Laver TW et al.

Diabetes, 2022

Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young.

Sun Y et al.

Journal of Diabetes Research, 2021

Tunisian Maturity-Onset Diabetes of the Young: A Short Review and a New Molecular and Clinical Investigation.

Moalla M et al.

Frontiers in Endocrinology, 2021

Genetic Testing of Maturity-Onset Diabetes of the Young Current Status and Future Perspectives.

Firdous P et al.

Frontiers in Endocrinology, 2018

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.

Lomberk G et al.

The Journal of Biological Chemistry, 2013

Genetic associations with diabetes: meta-analyses of 10 candidate polymorphisms.

Tang L et al.

Plos One, 2013

MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells.

Fernandez-Zapico ME et al.

The Journal of Biological Chemistry, 2009

Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese.

Kuroda E et al.

Endocrine Journal, 2009

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.

Ma L et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C.

Gutiérrez-Aguilar R et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes.

Vaxillaire M et al.

Endocrine Reviews, 2008

The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population.

Tanahashi T et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2008

The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.

Florez JC et al.

Diabetes, 2006

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.

Neve B et al.

Proceedings of the National Academy of Sciences of the United States of America, 2005

Cytokine Profile in Patients With Maturity-onset Diabetes of the Young (MODY).

Diren A et al.

In Vivo (athens, Greece), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."