Varaico: Literature-Extracted Genetic Variants

Gene:KLF11
Variant:p.T220M
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KLF11

NM_003597.5:p.T220M

Associated Papers

Novel Kruppel-like factor 11 variant of maturity-onset diabetes of the young type 7: A case report.

Alvarez M et al.

World Journal of Diabetes, 2025

Rare BLK, CEL, KLF11, PDX1, and PAX4 Gene Variants in Russian Patients with Monogenic Diabetes: Clinical and Molecular Characterization.

Khusainova RI et al.

Biomedicines, 2025

Novel gene mutation in maturity-onset diabetes of the young: A case report.

Zhang N et al.

World Journal of Clinical Cases, 2023

Genetic and Functional Analyses of the Novel KLF11 Pro193Thr Variant in a Three-Generation Family with MODY7.

Guan G et al.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 2023

Insights into the Genetics and Signaling Pathways in Maturity-Onset Diabetes of the Young.

Sousa M et al.

International Journal of Molecular Sciences, 2022

Maturity-Onset Diabetes of the Young: Mutations, Physiological Consequences, and Treatment Options.

Younis H et al.

Journal of Personalized Medicine, 2022

Early-onset diabetes involving three consecutive generations had different clinical features from age-matched type 2 diabetes without a family history in China.

Wang DW et al.

Endocrine, 2022

A novel KLF11 variant in a family with maturity-onset diabetes of the young.

Wu S et al.

Pediatric Diabetes, 2022

Precision Diagnosis of Maturity-Onset Diabetes of the Young with Next-Generation Sequencing: Findings from the MODY-IST Study in Adult Patients.

Aydogan HY et al.

Omics : a Journal of Integrative Biology, 2022

Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young.

Sun Y et al.

Journal of Diabetes Research, 2021

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.

Cao Y et al.

Cell Research, 2020

32355288 (PubMed )
Supplement: 41422_2020_322_MOESM14_ESM.xlsx › S7

Maturity-onset diabetes of the young: update and perspectives on diagnosis and treatment.

Jang KM

Yeungnam University Journal of Medicine, 2020

The GenomeAsia 100K Project enables genetic discoveries across Asia.

Unknown Author

Nature, 2019

31802016 (PubMed )
Supplement: 41586_2019_1793_MOESM3_ESM.xlsx › S4b_-_Disease_Var

KLF11 variant in a family clinically diagnosed with early childhood-onset type 1B diabetes.

Ushijima K et al.

Pediatric Diabetes, 2019

Monogenic diabetes in overweight and obese youth diagnosed with type 2 diabetes: the TODAY clinical trial.

Kleinberger JW et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2018

Genetic Testing of Maturity-Onset Diabetes of the Young Current Status and Future Perspectives.

Firdous P et al.

Frontiers in Endocrinology, 2018

Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar.

Rodriguez-Flores JL et al.

Human Mutation, 2014

Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.

Lomberk G et al.

The Journal of Biological Chemistry, 2013

MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells.

Fernandez-Zapico ME et al.

The Journal of Biological Chemistry, 2009

Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese.

Kuroda E et al.

Endocrine Journal, 2009

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.

Ma L et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

The association of genetic variants in Krüppel-like factor 11 and Type 2 diabetes in the Japanese population.

Tanahashi T et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2008

The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.

Florez JC et al.

Diabetes, 2006

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.

Neve B et al.

Proceedings of the National Academy of Sciences of the United States of America, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."