Associated Papers
Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms: A Review.
Mokhosoev IM et al.
Cells, 2024
A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer.
Srinivasan S et al.
Nature Communications, 2024
Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancer.
Srinivasan S et al.
Research Square, 2023
FinnGen provides genetic insights from a well-phenotyped isolated population.
Kurki MI et al.
Nature, 2023
KLK3 germline mutation I179T complements DNA repair genes for predicting prostate cancer progression.
Xu J et al.
Prostate Cancer and Prostatic Diseases, 2022
Targeted Mass Spectrometry of a Clinically Relevant PSA Variant from Post-DRE Urines for Quantitation and Genotype Determination.
Otto JJ et al.
Proteomics. Clinical Applications, 2020
Post-GWAS in prostate cancer: from genetic association to biological contribution.
Farashi S et al.
Nature Reviews. Cancer, 2019
Mutations in the prostate specific antigen (PSA/KLK3) correlate with male infertility.
Gupta N et al.
Scientific Reports, 2017
Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?
Srinivasan S et al.
Critical Reviews in Clinical Laboratory Sciences, 2016
An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality.
Sullivan J et al.
British Journal of Cancer, 2015
Mining for single nucleotide variants (SNVs) at the kallikrein locus with predicted functional consequences.
Sukumar N et al.
Biological Chemistry, 2014
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
Haiman CA et al.
Plos Genetics, 2013
Very low PSA concentrations and deletions of the KLK3 gene.
Rodriguez S et al.
Clinical Chemistry, 2013
Presence of antigen-specific somatic allelic mutations and splice variants do not predict for immunological response to genetic vaccination.
Becker JT et al.
Journal for Immunotherapy of Cancer, 2013
Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases.
Batra J et al.
Biological Chemistry, 2012
Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.
Parikh H et al.
Human Genetics, 2011
Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript.
Kote-Jarai Z et al.
Human Genetics, 2011
Genetic correction of PSA values using sequence variants associated with PSA levels.
Gudmundsson J et al.
Science Translational Medicine, 2010
A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.
Parikh H et al.
Human Genetics, 2010
The interaction of CYP3A5 polymorphisms along the androgen metabolism pathway in prostate cancer.
Vaarala MH et al.
International Journal of Cancer, 2008
A consolidated catalogue and graphical annotation of dbSNP polymorphisms in the human tissue kallikrein (KLK) locus.
Goard CA et al.
Molecular Oncology, 2007
Identification and analysis of deleterious human SNPs.
Yue P et al.
Journal of Molecular Biology, 2006
Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.
Mononen N et al.
Cancer Research, 2006