Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.I187V
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KRAS

NM_004985.5:p.I187V

Associated Papers

The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.

Ryan MB et al.

Cancer Discovery, 2024

38588399 (PubMed )
Supplement: cd-24-0139_supplementary_table_6_suppst6.xlsx › OMNI

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity.

Chen X et al.

Cancer Biology & Medicine, 2021

Sensitive and specific post-call filtering of genetic variants in xenograft and primary tumors.

Mannakee BK et al.

Bioinformatics (oxford, England), 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."