Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.K179R
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KRAS

NM_004985.5:p.K179R

Associated Papers

TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinoma.

Zhou Y et al.

Journal of Translational Medicine, 2023

38037073 (PubMed )
Supplement: 12967_2023_4742_MOESM3_ESM.xlsx › Sheet1

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Ramakrishnan G et al.

Cell Reports, 2022

36351408 (PubMed )
Supplement: NIHMS1848910-supplement-2.xlsx › NF1-_TP53

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures.

Georgeson P et al.

Nature Communications, 2022

35668106 (PubMed )
Supplement: 41467_2022_30916_MOESM1_ESM.pdf

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Somatic mutation profiling and HER2 status in KRAS-positive Chinese colorectal cancer patients.

Dong Z et al.

Scientific Reports, 2019

31729406 (PubMed )
Supplement: 41598_2019_53039_MOESM1_ESM.pdf

An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer.

Wang H et al.

Ebiomedicine, 2019

31668570 (PubMed )
Supplement: mmc4.xlsx › Sheet1

Molecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancer.

Tezcan G et al.

World Journal of Gastrointestinal Oncology, 2016

The genetic basis of familial adenomatous polyposis and its implications for clinical practice and risk management.

Leoz ML et al.

The Application of Clinical Genetics, 2015

Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.

Cai X et al.

Plos One, 2014

DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.

Berg M et al.

Plos One, 2010

21103049 (PubMed )
Supplement: pone.0013978.s002.xls › Table_S2
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."