Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.D154N
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KRAS

NM_004985.5:p.D154N

Associated Papers

Targeted therapy guided by circulating tumor DNA analysis in advanced gastrointestinal tumors.

Nakamura Y et al.

Nature Medicine, 2025

39284955 (PubMed )
Supplement: 41591_2024_3244_MOESM2_ESM.xlsx › Suppementary_Table_1

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_2.xlsx › TCGA_Germline_Somatic_coinciden

Increased KRAS G12C Prevalence, High Tumor Mutational Burden, and Specific Mutational Signatures Are Associated With MUTYH Mutations: A Pan-Cancer Analysis.

Disel U et al.

The Oncologist, 2024

37589222 (PubMed )
Supplement: oyad230_suppl_supplementary_tables.xlsx › Supplementary_Table_2

3DVizSNP: a tool for rapidly visualizing missense mutations identified in high throughput experiments in iCn3D.

Sierk M et al.

Bmc Bioinformatics, 2023

The role of next-generation sequencing in the examination of signaling genes in Brca1/2-negative breast cancer cases.

Cine N et al.

Annals of Human Genetics, 2023

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › RAS_Manuscript_RMarkdown.tar.gz › RAS_Manuscript1.Revised › RAS_Variants_Scores.xlsx › Sheet1

The Ras dimer structure.

Rudack T et al.

Chemical Science, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."