Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.A146G
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KRAS

NM_004985.5:p.A146G

Associated Papers

Performance and considerations in the use of diagnostic mutation panels for clonality testing in non-small-cell lung carcinoma.

Janssen J et al.

Esmo Open, 2025

40373350 (PubMed )
Supplement: mmc4.xlsx › 4c_Correctly_classified

Genomic Landscapes of Early-Onset Versus Average-Onset Colorectal Cancer Populations.

Storandt MH et al.

Cancers, 2025

40075683 (PubMed )
Supplement: cancers-17-00836-s001.zip › cancers-3446894-supplementary.pdf

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-1.pdf

Efficacy of Regorafenib and Trifluridine/Tipiracil According to Extended RAS Evaluation in Advanced Metastatic Colorectal Cancer Patients: A Multicenter Retrospective Analysis.

Basso M et al.

Targeted Oncology, 2024

Assessment of the Mutation Profile of Tonsillar Squamous Cell Carcinomas Using Targeted Next-Generation Sequencing.

Park HY et al.

Biomedicines, 2023

36979829 (PubMed )
Supplement: biomedicines-11-00851-s001.zip › biomedicines-2237878-supplementary.pdf

KRAS mutation as a predictor of insufficient trastuzumab efficacy and poor prognosis in HER2-positive advanced gastric cancer.

Shimozaki K et al.

Journal of Cancer Research and Clinical Oncology, 2023

Clinical Impact of Primary Tumor Location and RAS, BRAF V600E, and PIK3CA Mutations on Epidermal Growth Factor Receptor Inhibitor Efficacy as Third-line Chemotherapy for Metastatic Colorectal Cancer.

Sato T et al.

Anticancer Research, 2021

Positive Correlation Between Somatic Mutations in RAS Gene and Colorectal Cancer in Telangana Population: Hospital-Based Study in a Cosmopolitan City.

Goud KI et al.

Applied Biochemistry and Biotechnology, 2020

RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.

Osumi H et al.

International Journal of Cancer, 2016

A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer.

Kawazoe A et al.

Bmc Cancer, 2015

Clinical Implication of KRAS Mutation Variants in Patients With Resected Colon Cancer.

Baek JH et al.

Cancer Diagnosis & Prognosis, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."