Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.K117Q
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KRAS

NM_004985.5:p.K117Q

Associated Papers

Functional Analysis of Rare RAS Variants of Unknown Significance.

Park S et al.

Cancer Research Communications, 2025

40970755 (PubMed )
Supplement: crc-25-0188_supplementary_table_s5_suppst5.xlsx › Supplementary_Table_S5

Coevolution of Atypical BRAF and KRAS Mutations in Colorectal Tumorigenesis.

Woolley CE et al.

Molecular Cancer Research : Mcr, 2025

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-1.pdf

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Magits W et al.

The Embo Journal, 2024

38858602 (PubMed )
Supplement: 44318_2024_146_MOESM2_ESM.pdf

BMP4 and PHLDA1 are plausible drug-targetable candidate genes for KRAS G12A-, G12D-, and G12V-driven colorectal cancer.

Ohnami S et al.

Molecular and Cellular Biochemistry, 2021

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