Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.E98*
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KRAS

NM_004985.5:p.E98*

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers.

De Angelis MT et al.

Journal of Translational Medicine, 2025

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_2.xlsx › TCGA_Germline_Somatic_coinciden

An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness.

Szafron LA et al.

International Journal of Molecular Sciences, 2024

39456660 (PubMed )
Supplement: ijms-25-10876-s001.zip › Supplement-variants.xlsx › Hot.spot.panel.SNP_all_variants

KRAS mutated colorectal cancers with or without PIK3CA mutations: Clinical and molecular profiles inform current and future therapeutics.

Voutsadakis IA

Critical Reviews in Oncology/hematology, 2023

High prevalence of unusual KRAS, NRAS, and BRAF mutations in POLE-hypermutated colorectal cancers.

Favre L et al.

Molecular Oncology, 2022

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer.

Loree JM et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2021

Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

Temko D et al.

The Journal of Pathology, 2018

29604063 (PubMed )
Supplement: PATH-245-283-s022.xlsx › CRC.Drivers.Edited

Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Kong SL et al.

Oncotarget, 2017

28978093 (PubMed )
Supplement: oncotarget-08-68026-s002.xlsx › Table_S5

Next-generation sequencing adds value to the preoperative diagnosis of pancreatic cysts.

Rosenbaum MW et al.

Cancer Cytopathology, 2017

Impact of genomic profiling on the treatment and outcomes of patients with advanced gastrointestinal malignancies.

Dhir M et al.

Cancer Medicine, 2017

28028924 (PubMed )
Supplement: CAM4-6-195-s001.xlsx › Sheet1

Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts.

Jones M et al.

Gastrointestinal Endoscopy, 2016

High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Tan IB et al.

Genome Biology, 2015

25808843 (PubMed )
Supplement: 13059_2015_589_MOESM4_ESM.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."