Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.R97I
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KRAS

NM_004985.5:p.R97I

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.

Holderfield M et al.

Nature, 2024

38589574 (PubMed )
Supplement: 41586_2024_7205_MOESM5_ESM.xlsx › Additional_Cell_Panel_Data

Allosteric site variants affect GTP hydrolysis on Ras.

Johnson CW et al.

Protein Science : a Publication of the Protein Society, 2023

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › RAS_Manuscript_RMarkdown.tar.gz › RAS_Manuscript1.Revised › RAS_Variants_Scores.xlsx › Sheet1

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.

Melloni GE et al.

Bmc Bioinformatics, 2016

26860319 (PubMed )
Supplement: 12859_2016_935_MOESM2_ESM.xlsx › Table_S5
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."