Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.F82L
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KRAS

NM_004985.5:p.F82L

Associated Papers

The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.

Ryan MB et al.

Cancer Discovery, 2024

38588399 (PubMed )
Supplement: cd-24-0139_supplementary_table_6_suppst6.xlsx › OMNI

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.

Flümann R et al.

Blood Cancer Discovery, 2023

36346827 (PubMed )
Supplement: bcd-22-0007_table_s6_suppst6.xlsx › F_Mut_Pat.__6

KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Vendramini E et al.

Cancers, 2022

appreci8: a pipeline for precise variant calling integrating 8 tools.

Sandmann S et al.

Bioinformatics (oxford, England), 2018

29945233 (PubMed )
Supplement: bty518_supplementary_data_s10.xlsx › TN_Mutations_Filter_1

Recent advances in RASopathies.

Aoki Y et al.

Journal of Human Genetics, 2016

Oncogenic RIT1 mutations in lung adenocarcinoma.

Berger AH et al.

Oncogene, 2014

24469055 (PubMed )
Supplement: 41388_2014_BFonc2013581_MOESM15_ESM.pdf

Cutaneous epithelial tumors induced by vemurafenib involve the MAPK and Pi3KCA pathways but not HPV nor HPyV viral infection.

Frouin E et al.

Plos One, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."