Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.C80S
Back to variants list

KRAS

NM_004985.5:p.C80S

Associated Papers

Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS.

van Tienen LM et al.

Cell Chemical Biology, 2026

Functional Analysis of Rare RAS Variants of Unknown Significance.

Park S et al.

Cancer Research Communications, 2025

40970755 (PubMed )
Supplement: crc-25-0188_supplementary_table_s5_suppst5.xlsx › Supplementary_Table_S5

The structure of KRASG12C bound to divarasib highlights features of potent switch-II pocket engagement.

Fernando MC et al.

Small Gtpases, 2024

Predicting the effects of rare genetic variants on oncogenic signaling pathways: A computational analysis of HRAS protein function.

Ali S et al.

Frontiers in Chemistry, 2023

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › RAS_Manuscript_RMarkdown.tar.gz › RAS_Manuscript1.Revised › RAS_Variants_Scores.xlsx › Sheet1
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."