Associated Papers
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.
Kwon JJ et al.
Biorxiv : the Preprint Server for Biology, 2024
39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen
Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway.
Vaqué JP et al.
The Journal of Biological Chemistry, 2005
Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant.
Wittinghofer F et al.
Environmental Health Perspectives, 1991
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