Associated Papers
Structural insights into non-hotspot KRAS mutations and their potential as targets for effective cancer therapies.
Ding C et al.
Journal of Biomolecular Structure & Dynamics, 2025
Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation.
Czyzyk D et al.
Nature Communications, 2025
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.
Kwon JJ et al.
Biorxiv : the Preprint Server for Biology, 2024
39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen
Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.
Tripathi S et al.
Bioinformatics (oxford, England), 2021
Phenotypic characterization of the novel, non-hotspot oncogenic KRAS mutants E31D and E63K.
Angeles AKJ et al.
Oncology Letters, 2019
Select a paper to view details