Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.E31K
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KRAS

NM_004985.5:p.E31K

Associated Papers

Prognostic Significance of SOX9 and Its Combination With RAS and TP53 Mutations Following Colorectal Cancer Liver Metastasectomy.

Duan JL et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2025

TP53 c.730G > A pathogenic variant as a plausible candidate biomarker in pancreatic ductal adenocarcinoma patients from Karachi, pakistan: a retrospective cohort study.

Ali SMA et al.

Bmc Cancer, 2025

Functional Analysis of Rare RAS Variants of Unknown Significance.

Park S et al.

Cancer Research Communications, 2025

40970755 (PubMed )
Supplement: crc-25-0188_supplementary_table_s5_suppst5.xlsx › Supplementary_Table_S5

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen

Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity.

Shah SM et al.

Cancer Research Communications, 2024

38282550 (PubMed )
Supplement: crc-23-0312-s02.xlsx › Fig3A_CRC_data

β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53.

Bourmoum M et al.

Plos One, 2024

38324534 (PubMed )
Supplement: pone.0295030.s003.xlsx › 3samples.exome.dp5.snvindel

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Vendramini E et al.

Cancers, 2022

Discovery of a novel and a rare Kristen rat sarcoma viral oncogene homolog (KRAS) gene mutation in colorectal cancer patients.

Rasool M et al.

Bioengineered, 2021

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer.

Loree JM et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2021

RAS as a positive predictive biomarker: focus on lung and colorectal cancer patients.

Malapelle U et al.

European Journal of Cancer (oxford, England : 1990), 2021

KRAS G12C mutations in Asia: a landscape analysis of 11,951 Chinese tumor samples.

Loong HH et al.

Translational Lung Cancer Research, 2020

Atypical RAS Mutations in Metastatic Colorectal Cancer.

Pietrantonio F et al.

Jco Precision Oncology, 2019

Molecular association of functioning stroma with carcinoma cells in the ovary: A preliminary study.

Narikiyo M et al.

Oncology Letters, 2019

A Comparative Analysis of Individual RAS Mutations in Cancer Biology.

Muñoz-Maldonado C et al.

Frontiers in Oncology, 2019

Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.

Cho SY et al.

Gastroenterology, 2017

28522256 (PubMed )
Supplement: NIHMS1058936-supplement-Table_S3.xlsx › VCF

Influence of mucinous and necrotic tissue in colorectal cancer samples on KRAS mutation analysis.

Büttner J et al.

Pathology, Research and Practice, 2017

Circumscribed sebaceous neoplasms: a morphological, immunohistochemical and molecular analysis.

Harvey NT et al.

Pathology, 2016

Driver Gene Mutations in Stools of Colorectal Carcinoma Patients Detected by Targeted Next-Generation Sequencing.

Armengol G et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Intratumoral KIT mutational heterogeneity and recurrent KIT/ PDGFRA mutations in KIT/PDGFRA wild-type gastrointestinal stromal tumors.

Gao J et al.

Oncotarget, 2016

26848617 (PubMed )
Supplement: oncotarget-07-30241-s002.xlsx › Sheet1

Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Kim EY et al.

Bmc Cancer, 2016

26782967 (PubMed )
Supplement: 12885_2016_2049_MOESM1_ESM.xlsx › Sheet1

GTP-Dependent K-Ras Dimerization.

Muratcioglu S et al.

Structure (london, England : 1993), 2015

Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.

Alakus H et al.

Genome Medicine, 2014

24944587 (PubMed )
Supplement: gm559-S3.xls › Table_S11

Genomic and biological characterization of exon 4 KRAS mutations in human cancer.

Janakiraman M et al.

Cancer Research, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."