Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.T20T
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KRAS

NM_004985.5:p.T20T

Associated Papers

Performance and considerations in the use of diagnostic mutation panels for clonality testing in non-small-cell lung carcinoma.

Janssen J et al.

Esmo Open, 2025

40373350 (PubMed )
Supplement: mmc4.xlsx › 4c_Correctly_classified

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_3.xlsx › KRAS_G12D_LOF_DMS_Screens

Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins.

Wang Y et al.

Computational and Structural Biotechnology Journal, 2021

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Brown AL et al.

Plos Computational Biology, 2019

31034466 (PubMed )
Supplement: pcbi.1006981.s010.xlsx › final_benchmark

The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.

Lu S et al.

Scientific Reports, 2016

Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences.

Chakrabarti M et al.

The Journal of Physical Chemistry. B, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."