Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.K16M
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KRAS

NM_004985.5:p.K16M

Associated Papers

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen

Understanding the influence of AMG 510 on the structure of KRASG12C empowered by molecular dynamics simulation.

Li Y et al.

Computational and Structural Biotechnology Journal, 2022

35284050 (PubMed )
Supplement: mmc1.docx

SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.

Xue Y et al.

Nature Communications, 2019

30718506 (PubMed )
Supplement: 41467_2019_8380_MOESM3_ESM.xlsx › Supplemental_Table_1

Selective identification of somatic mutations in pancreatic cancer cells through a combination of next-generation sequencing of plasma DNA using molecular barcodes and a bioinformatic variant filter.

Kukita Y et al.

Plos One, 2018

29451897 (PubMed )
Supplement: pone.0192611.s007.xlsx › tableSX
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."