Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.K16E
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KRAS

NM_004985.5:p.K16E

Associated Papers

Pathogenic Proteins Through the Lens of NMR Spectroscopy: Structural and Functional Insights into Disease.

Aboalroub AA

Cell Biochemistry and Biophysics, 2025

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen

Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing.

Sayed S et al.

Cancer Research, 2022

Understanding the influence of AMG 510 on the structure of KRASG12C empowered by molecular dynamics simulation.

Li Y et al.

Computational and Structural Biotechnology Journal, 2022

35284050 (PubMed )
Supplement: mmc1.docx

K-Ras G-domain binding with signaling lipid phosphatidylinositol (4,5)-phosphate (PIP2): membrane association, protein orientation, and function.

Cao S et al.

The Journal of Biological Chemistry, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."