Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.G15C
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KRAS

NM_004985.5:p.G15C

Associated Papers

Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS.

van Tienen LM et al.

Cell Chemical Biology, 2026

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen

Personalized drug screening using patient-derived organoid and its clinical relevance in gastric cancer.

Zhao Y et al.

Cell Reports. Medicine, 2024

38964315 (PubMed )
Supplement: mmc3.pdf

Molecular Divergence upon EGFR-TKI Resistance Could Be Dependent on the Exon Location of the Original EGFR-Sensitizing Mutation.

Serna-Blasco R et al.

Cancers, 2022

36139605 (PubMed )
Supplement: cancers-14-04446-s001.zip › Supplemental_data_S2.xlsx › dPCR_assays

High-resolution melting for detecting KRAS mutations in colorectal cancer.

Miranda RR et al.

Biomedical Reports, 2019

Mutational analysis of KRAS and its clinical implications in cervical cancer patients.

Jiang W et al.

Journal of Gynecologic Oncology, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."