Varaico: Literature-Extracted Genetic Variants

Gene:KRAS
Variant:p.V14A
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KRAS

NM_004985.5:p.V14A

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_10

Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.

Kwon JJ et al.

Biorxiv : the Preprint Server for Biology, 2024

39484452 (PubMed )
Supplement: media-2.zip › Extended_Data_Tables › Extended_Data_Table_1.xlsx › KRAS_GOF_DMS_Screen

MEK Inhibition in a Pilocytic Astrocytoma With a Rare KRAS Q61R Mutation in a Young Adult Patient: A Case Report.

Roberto K et al.

Jco Precision Oncology, 2024

Riok1, A Novel Potential Target in MSI-High p53 Mutant Colorectal Cancer Cells.

Shechter S et al.

Molecules (basel, Switzerland), 2023

The status of KRAS mutations in primary ovarian clear cell carcinoma: An analysis of 17 Taiwanese patients.

Wang PC et al.

Taiwanese Journal of Obstetrics & Gynecology, 2023

Infrequent RAS mutation is not associated with specific histological phenotype in gliomas.

Makino Y et al.

Bmc Cancer, 2021

Statin-mediated inhibition of RAS prenylation activates ER stress to enhance the immunogenicity of KRAS mutant cancer.

Nam GH et al.

Journal for Immunotherapy of Cancer, 2021

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.

Reinhardt A et al.

Acta Neuropathologica, 2018

Somatic mutation analysis of KRAS, BRAF, HER2 and PTEN in EGFR mutation-negative non-small cell lung carcinoma: determination of frequency, distribution pattern and identification of novel deletion in HER2 gene from Indian patients.

Bhaumik S et al.

Medical Oncology (northwood, London, England), 2016

High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.

Ney JT et al.

Archives of Pathology & Laboratory Medicine, 2012

KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.

Mao C et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."