Associated Papers
Malignant adenomyoepithelioma with HRAS G13R mutation: A case report.
Kuwabara H et al.
Oncology Letters, 2026
Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol.
Spiekman IAC et al.
International Journal of Cancer, 2026
The evolving genetic landscape of ILVEN: A comprehensive review.
Aghajani M et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2026
The role of the kynurenine pathway in the pathophysiology of autism-like phenotype induced by maternal inflammation in male mice.
Santana-Coelho D et al.
Neurobiology of Disease, 2026
Deciphering gain-of-function from loss-of-function variants with AlphaMissense: A case study with the mechanosensitive PIEZO1 ion channel protein.
Pillai J et al.
Biochemistry and Biophysics Reports, 2026
Genetic analysis of key players in PI3K signaling cascade of colorectal carcinoma.
Pervaiz H et al.
Scientific Reports, 2026
Non-Isolated Dandy-Walker Malformation: Exome Sequencing Efficacy and Phenotypic Expansions.
Araji S et al.
Clinical Genetics, 2026
Impact of KRAS-G12 Mutations on the KRAS-GTP Bound Conformational Dynamics: Structure, Free Energy Barriers and Drugging Pockets.
Hu Z et al.
Jacs Au, 2026
Molecular features in gangliogliomas: a systematic review.
Pereira BJA et al.
Child's Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery, 2026
Database of recurrent mutations, an unbiased web resource to browse recurrent mutations in cancers.
Chakroborty D et al.
Iscience, 2026
A multiplex, prime editing framework for identifying drug resistance variants at scale.
Abadie FMC et al.
Cell Genomics, 2026
Daraxonrasib (RMC-6236) is an effective targeted therapy for RAS -mutant neuroblastoma.
Hill RD et al.
Biorxiv : the Preprint Server for Biology, 2026
Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS.
van Tienen LM et al.
Cell Chemical Biology, 2026
An Insulin-Exosome-TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer.
Li Z et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2026
Radiotherapy disrupts ferroptosis tolerance by reducing DNMT1 levels and uncouples STING silencing in LKB1-deficient lung tumors.
Zhang YP et al.
Free Radical Biology & Medicine, 2026
Deletion 9p drives B-ALL through the heterozygous inactivation of Pax5 and Cd72 in pre-leukemic cells.
Ruiz-Corzo B et al.
Jci Insight, 2026
A scalable approach to resolving variants of uncertain significance.
Tejura M et al.
Biorxiv : the Preprint Server for Biology, 2026
Coexistent PTEN and PIK3CA alterations hyperactivate mTORC1 signaling in endometrial cancers and cause their selective sensitivity to mTORC1 inhibition.
Solomon H et al.
Biorxiv : the Preprint Server for Biology, 2026
Ras-Related Mutants Identified in Young-Onset Colorectal Cancer Display Divergent Phenotypes and Retain Their Pro-Angiogenic Effects.
David APL et al.
Cells, 2026
A CRISPR/Cas9-regulated dual-ring topological allosteric probe for detection of the EGFR L858R resistance mutation in CTCs.
Wang C et al.
Analytical Methods : Advancing Methods and Applications, 2026
Association of germline variants with KRAS-mutation status in colorectal cancer.
Tjader NP et al.
Scientific Reports, 2026
Differential Preclinical Efficacy of Combined CDK4/6 and MEK Inhibition in Low-Grade Serous Ovarian Carcinoma Based on KRAS/NF1 Mutational Status.
Bittner M et al.
International Journal of Molecular Sciences, 2026
Genomic alterations and their correlation with metabolic-related genes in lung cancer.
Gaur G et al.
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026
The Role and Impact of Non-driver Gene Mutations in Myelofibrosis.
Boldrini V et al.
Current Hematologic Malignancy Reports, 2026
Clinico-genomic characterization of RAS-mutant acute myeloid leukemia.
Yuan R et al.
Annals of Hematology, 2026
Metabolic permissiveness: how tissue context shapes cancer.
Moschandrea C et al.
Genes & Development, 2026
Genomic Profile of Non-Small Cell Lung Cancer in a Spanish Cohort: A 2-Year Descriptive Study Using Next-Generation Sequencing.
Carnero-Gregorio M et al.
Genes, 2026
Negative Selection Maintains Grossly Altered but Broadly Stable Karyotypes in Metastatic Colorectal Cancer.
Cross WCH et al.
Cancer Discovery, 2026
Rare, Yet Targetable: New Perspectives on Ampullary Carcinomas.
Gutmans J et al.
International Journal of Molecular Sciences, 2026
Health Care Impact of Comprehensive Genomic Profiling of Solid Tumors in Patient Management Using POWER (Precision Oncology at Western University).
Bhai P et al.
The Journal of Molecular Diagnostics : Jmd, 2026
Precision oncology in Bulgaria: a prospective study of metastatic colorectal cancer patients.
Dimitrov G et al.
Cancer Treatment and Research Communications, 2026
Attenuated Li-Fraumeni syndrome with TP53 p.R181H in a Japanese patient with metastatic rectal adenocarcinoma: a case report.
Kasahara Y et al.
Familial Cancer, 2026
TGFB-inducible VASN (vasorin) promotes lysosomal acidification.
Yan J et al.
Autophagy, 2026
Clinicopathologic and Molecular Features of Tubo-Ovarian Carcinosarcomas with an Emphasis on p53 Wild-Type, KRAS-Mutated Tumors.
Hammer PM et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2026
Novel interlock probe-driven ligation-mediated PCR platform for ultra-specific detection of low-frequency single-nucleotide variation.
Li X et al.
Talanta, 2026
Current opinions on Noonan syndrome and RASopathies.
Weaver KN et al.
Current Opinion in Pediatrics, 2026
Molecular Relationship Between Ovarian Sertoli-Leydig Cell Tumors and Their Heterologous Elements: Emphasis on the Possible Prognostic Significance of TERT Pathogenic Variants.
Trecourt A et al.
The American Journal of Surgical Pathology, 2026
Novel Syngeneic Cell Lines for Studying High-Risk BRAFV600E-Driven Colorectal Cancer In Vivo.
Traichel J et al.
Cancer Research Communications, 2026
Histomorphological and Molecular Features of Colonic Large-Cell Neuroendocrine Carcinoma in a Patient With Familial Adenomatous Polyposis: A Case Report and Review of Literature.
Moustafa M et al.
International Journal of Surgical Pathology, 2026
Patient-specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity.
Strecker M et al.
Molecular Oncology, 2026
Intestinal LKB1 Loss Drives a Premalignant Program Along the Serrated Cancer Pathway.
Plugge SF et al.
Gastroenterology, 2026
Histopathological associations, molecular findings and clinical outcomes of patients with non-small cell lung carcinoma with MET alterations: a 3-year retrospective Australian case series.
Li JJ et al.
Pathology, 2026
Transgelin defines pro-tumorigenic cancer-associated fibroblasts in pancreatic cancer.
Wang X et al.
British Journal of Cancer, 2026
Identifying and capitalizing on unique molecular alterations of mucinous ovarian carcinoma for the development of novel therapeutic strategies.
Jang M et al.
Gynecologic Oncology Reports, 2026
Insights into RAS-driven melanoma and its therapeutic implications.
Chatziioannou E et al.
Cancer Treatment Reviews, 2026
Targeting oncogenic K-RAS mutants with small-molecule degrader XMU-MP-9 through NEDD4-1.
Zeng T et al.
Acta Pharmaceutica Sinica. B, 2026
Tutorial for variant interrogation in tumor samples.
Arseneau RJ et al.
Plos Computational Biology, 2026
Synonymous Variants of Potential Significance Identified by a 52-Gene Clinical Sequencing Panel in Non-Small Cell Lung Cancer.
Varty K et al.
Genes, Chromosomes & Cancer, 2026
Prognostic Implications of Codon-Specific KRAS Mutations in Localized and Advanced Stages of Pancreatic Cancer.
Raji S et al.
Jco Precision Oncology, 2026