Varaico: Literature-Extracted Genetic Variants

Gene:LACC1
Variant:p.K38E
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LACC1

NM_153218.4:p.K38E

Associated Papers

Crohn's Disease-associated variant in laccase domain containing 1 (LACC1) modulates T cell gene expression, metabolism and T cell function.

Li Y et al.

Nature Communications, 2025

40089498 (PubMed )
Supplement: 41467_2025_57744_MOESM6_ESM.pdf

LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages.

Wei Z et al.

Nature, 2022

Biallelic loss-of-function LACC1/FAMIN Mutations Presenting as Rheumatoid Factor-Negative Polyarticular Juvenile Idiopathic Arthritis.

Rabionet R et al.

Scientific Reports, 2019

LACC1 polymorphisms in inflammatory bowel disease and juvenile idiopathic arthritis.

Assadi G et al.

Genes and Immunity, 2016

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

Rivas MA et al.

Nature Genetics, 2011

21983784 (PubMed )
Supplement: NIHMS335188-supplement-1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."