Varaico: Literature-Extracted Genetic Variants

Gene:LCK
Variant:p.P26R
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LCK

NM_005356.5:p.P26R

Associated Papers

Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.

Pokoyski C et al.

Genes and Immunity, 2015

Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells.

Windhagen A et al.

Clinical and Experimental Immunology, 2007

Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection.

Dawes R et al.

Journal of Medical Genetics, 2006

Altered CD45 expression and disease.

Tchilian EZ et al.

Trends in Immunology, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."