Varaico: Literature-Extracted Genetic Variants

Gene:LCOR
Variant:p.E78D
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LCOR

NM_001346516.2:p.E78D

Associated Papers

Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain.

Huber BR et al.

Molecular Endocrinology (baltimore, Md.), 2003

A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone.

Collingwood TN et al.

The Embo Journal, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."