Associated Papers
LDLR variant classification through activity-normalized prime editing screening.
Zhou PJ et al.
Biorxiv : the Preprint Server for Biology, 2025
41473288 (PubMed )
Supplement: media-2.xlsx › SuppTable2
IDOL G51S Variant Is Associated With High Blood Cholesterol and Increases Low-Density Lipoprotein Receptor Degradation.
Adi D et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2019
31597442 (PubMed )
Supplement: atvb_atvb-2019-312589_supp2.pdf
Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL).
Sorrentino V et al.
The Journal of Biological Chemistry, 2011
The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.
Hong C et al.
The Journal of Biological Chemistry, 2010
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