Varaico: Literature-Extracted Genetic Variants

Gene:LEP
Variant:p.F62C
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LEP

NM_000230.3:p.F62C

Associated Papers

Exploring Autosomal Dominant Non-Syndromic Monogenic Obesity: From Genes to Therapy.

Luppino G et al.

Current Issues in Molecular Biology, 2026

Association of Mutations in the Melanocortin-2 Receptor Accessory Protein 2 Gene (MRAP2) and Obesity: A Systematic Review and Meta-Analysis.

Ji RL et al.

International Journal of Molecular Sciences, 2026

Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways.

Wyatt RA et al.

Human Molecular Genetics, 2025

Study of LEP, MRAP2 and POMC genes as potential causes of severe obesity in Brazilian patients.

da Fonseca ACP et al.

Eating and Weight Disorders : Ewd, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."