Associated Papers
Medical semiology of patients with monogenic obesity: A systematic review.
Renard E et al.
Obesity Reviews : an Official Journal of the International Association for the Study of Obesity, 2024
A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies.
Baird HJM et al.
The Journal of Biological Chemistry, 2024
Targeted gene panel provides advantages over whole-exome sequencing for diagnosing obesity and diabetes mellitus.
Yu H et al.
Journal of Molecular Cell Biology, 2023
Leptin Signaling in Obesity and Colorectal Cancer.
Socol CT et al.
International Journal of Molecular Sciences, 2022
Prevalence estimates of putatively pathogenic leptin variants in the gnomAD database.
Rajcsanyi LS et al.
Plos One, 2022
A Case-Control Study of the Association of Leptin Gene Polymorphisms with Plasma Leptin Levels and Obesity in the Kerala Population.
Manju SK et al.
Journal of Obesity, 2022
A fresh look to the phenotype in mono-allelic likely pathogenic variants of the leptin and the leptin receptor gene.
Koerber-Rosso I et al.
Molecular and Cellular Pediatrics, 2021
ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin.
Hong CJ et al.
Plos One, 2010
No association of LEPR Gln223Arg polymorphism with leptin, obesity or metabolic disturbances in children.
Pyrzak B et al.
European Journal of Medical Research, 2009
Understanding mutations and protein stability through tripeptides.
Anishetty S et al.
Febs Letters, 2006
Genetics of leptin and obesity: a HuGE review.
Paracchini V et al.
American Journal of Epidemiology, 2005
A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus.
Watanabe I et al.
Clinical Pharmacology and Therapeutics, 2003
A polymorphic marker in the leptin gene associated with Japanese morbid obesity.
Ohshiro Y et al.
Journal of Molecular Medicine (berlin, Germany), 2000
Identification of new sequence variants in the leptin gene.
Karvonen MK et al.
The Journal of Clinical Endocrinology and Metabolism, 1998
Identification of two novel missense mutations in the human OB gene.
Echwald SM et al.
International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 1997