Varaico: Literature-Extracted Genetic Variants

Gene:LEPR
Variant:p.S75G
Back to variants list

LEPR

NM_002303.6:p.S75G

Associated Papers

Meta-analysis investigating the impact of the LEPR rs1137101 (A>G) polymorphism on obesity risk in Asian and Caucasian ethnicities.

Supti DA et al.

Heliyon, 2024

38496879 (PubMed )
Supplement: mmc1.docx

Association between genetic polymorphisms of leptin receptor and preeclampsia in Chinese women.

Zeng S et al.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2023

Pharmacogenomics of response to statin treatment and susceptibility to statin-induced adverse drug reactions in Asians: a scoping review.

Yow HY et al.

Asian Biomedicine : Research, Reviews and News, 2023

GHRL, LEP, LEPR genes polymorphism and their association with the metabolic syndrome in the Ukrainian population.

Prodan A et al.

Endocrine Regulations, 2023

Genetics of Familial Combined Hyperlipidemia (FCHL) Disorder: An Update.

Taghizadeh E et al.

Biochemical Genetics, 2022

Computational and artificial neural network based study of functional SNPs of human LEPR protein associated with reproductive function.

Gandhi Muruganandhan S et al.

Journal of Cellular Biochemistry, 2019

Leptin Gene G2548A Polymorphism among Mongolians with Metabolic Syndrome.

Dagdan B et al.

Medical Sciences (basel, Switzerland), 2018

Association of polymorphisms of leptin, leptin receptor and apelin receptor genes with susceptibility to coronary artery disease and hypertension.

Nowzari Z et al.

Life Sciences, 2018

Obesity phenotype in relation to gene polymorphism among samples of Egyptian children and their mothers.

Hassan NE et al.

Genes & Diseases, 2018

LEPR gene polymorphism and plasma soluble leptin receptor levels are associated with polycystic ovary syndrome in Han Chinese women.

Tu X et al.

Personalized Medicine, 2017

High-Carbohydrate/Low-Fat Diet-Induced Gender-Specific Serum Lipid Profile Changes Are Associated with LEPR Polymorphisms in Chinese Youth.

Tang H et al.

Annals of Nutrition & Metabolism, 2017

Genetic variation in leptin and leptin receptor genes is a risk factor for idiopathic recurrent spontaneous abortion.

Müller A et al.

Croatian Medical Journal, 2016

Maternal and neonatal leptin and leptin receptor polymorphisms associated with preterm birth.

Salem H et al.

Gene, 2016

Polymorphism in Leptin and Leptin Receptor Genes May Modify Leptin Levels and Represent Risk Factors for Multiple Sclerosis.

Farrokhi M et al.

Immunological Investigations, 2016

Correlations Between Leptin Gene Polymorphisms 223 A/G, 1019 G/A, 492 G/C, 976 C/A, and Anthropometrical and Biochemical Parameters in Children With Obesity: A Prospective Case-Control Study in a Romanian Population-The Nutrichild Study.

Mărginean CO et al.

Medicine, 2016

Association of LEPR Gln223Arg polymorphism with T2DM: A meta-analysis.

Liu Y et al.

Diabetes Research and Clinical Practice, 2015

Association of Leptin Receptor Gene Polymorphisms with Genetic Susceptibility to Ischemic Stroke.

Tang H et al.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2015

Maternal genotype and severe preeclampsia: a HuGE review.

Fong FM et al.

American Journal of Epidemiology, 2014

Genetic aspects of preeclampsia and the HELLP syndrome.

Haram K et al.

Journal of Pregnancy, 2014

Association of the 223A/G LEPR polymorphism with serum leptin levels in Iranian subjects with type 2 diabetes.

Mohammadzadeh G et al.

Archives of Iranian Medicine, 2013

Relationship between leptin receptor and polycystic ovary syndrome.

Li L et al.

Gene, 2013

Leptin and leptin receptor polymorphisms and recurrent pregnancy loss.

Chin JR et al.

Journal of Perinatology : Official Journal of the California Perinatal Association, 2013

Lipid-lowing pharmacogenomics in Chinese patients.

Hu M et al.

Expert Review of Cardiovascular Therapy, 2013

High leptin level and leptin receptor Lys656Asn variant are risk factors for preeclampsia.

Wang S et al.

Genetics and Molecular Research : Gmr, 2013

Association of Gln223Arg polymorphism of the leptin receptor with hypertensive left ventricular hypertrophy.

Zheng H et al.

Folia Biologica, 2013

The 223A>G polymorphism of the leptin receptor gene is associated with macroangiopathy in type 2 diabetes mellitus.

Gan RT et al.

Molecular Biology Reports, 2012

Study of leptin levels and gene polymorphisms in patients with central precocious puberty.

Su PH et al.

Pediatric Research, 2012

[Association of leptin level and leptin receptor gene polymorphisms with susceptibility to severe pre-eclampsia].

Guan LX et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2011

Leptin and leptin receptor polymorphisms are associated with poor outcome (death) in patients with non-appendicular secondary peritonitis.

Bracho-Riquelme RL et al.

Critical Care (london, England), 2011

Leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analysis.

Várkonyi T et al.

Bmc Medical Genetics, 2010

No association of LEPR Gln223Arg polymorphism with leptin, obesity or metabolic disturbances in children.

Pyrzak B et al.

European Journal of Medical Research, 2009

The 223A>G polymorphism of the leptin receptor gene and lipid-lowering efficacy of simvastatin in Chinese patients with coronary heart disease.

Sun YM et al.

European Journal of Clinical Pharmacology, 2009

Leptin receptor gene polymorphisms in severely pre-eclamptic women.

Rigó J et al.

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2006

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."