Varaico: Literature-Extracted Genetic Variants

Gene:LEPR
Variant:p.Y1141F
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LEPR

NM_002303.6:p.Y1141F

Associated Papers

Functional characterization of all missense variants in LEPR, PCSK1, and POMC genes arising from single-nucleotide variants.

Shah BP et al.

Expert Review of Endocrinology & Metabolism, 2023

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization.

White DW et al.

The Journal of Biological Chemistry, 1997

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

Baumann H et al.

Proceedings of the National Academy of Sciences of the United States of America, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."