Associated Papers
A novel LGI1 mutation causing autosomal dominant lateral temporal lobe epilepsy confirmed by a precise knock-in mouse model.
Hu P et al.
Cns Neuroscience & Therapeutics, 2022
The LGI1 protein: molecular structure, physiological functions and disruption-related seizures.
Baudin P et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Insights into the mechanisms of epilepsy from structural biology of LGI1-ADAM22.
Yamagata A et al.
Cellular and Molecular Life Sciences : Cmls, 2020
Structural insights into leucine-rich repeat-containing synaptic cleft molecules.
Yamagata A et al.
Current Opinion in Structural Biology, 2019
Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Yamagata A et al.
Nature Communications, 2018
Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation.
Traynelis J et al.
Genome Research, 2017
ExACtly zero or once: A clinically helpful guide to assessing genetic variants in mild epilepsies.
Bennett CA et al.
Neurology. Genetics, 2017
The clinical phenotype of autosomal dominant lateral temporal lobe epilepsy related to reelin mutations.
Michelucci R et al.
Epilepsy & Behavior : E&b, 2017
Genetic models of focal epilepsies.
Boillot M et al.
Journal of Neuroscience Methods, 2016
Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation.
Kesim YF et al.
Epilepsy Research, 2016
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Yokoi N et al.
Nature Medicine, 2015
A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy.
Lee MK et al.
Seizure, 2014
Hyperactive behavior in a family with autosomal dominant lateral temporal lobe epilepsy caused by a mutation in the LGI1/epitempin gene.
Berghuis B et al.
Epilepsy & Behavior : E&b, 2013
A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.
Leonardi E et al.
Plos One, 2011
LGI1 mutations in autosomal dominant and sporadic lateral temporal epilepsy.
Nobile C et al.
Human Mutation, 2009
Penetrance of LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Rosanoff MJ et al.
Neurology, 2008
Somatic alterations in brain tumors.
Barnholtz-Sloan J et al.
Oncology Reports, 2008
Genetic etiology of new forms of familial epilepsy.
Wang X et al.
Frontiers in Bioscience : a Journal and Virtual Library, 2008
The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface.
Sirerol-Piquer MS et al.
Human Molecular Genetics, 2006
Speech-induced aphasic seizures in epilepsy caused by LGI1 mutation.
Brodtkorb E et al.
Epilepsia, 2005
LGI1: a gene involved in epileptogenesis and glioma progression?
Gu W et al.
Neurogenetics, 2005
LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Ottman R et al.
Neurology, 2004
Autosomal dominant lateral temporal epilepsy: clinical spectrum, new epitempin mutations, and genetic heterogeneity in seven European families.
Michelucci R et al.
Epilepsia, 2003
Novel LGI1 mutation in a family with autosomal dominant partial epilepsy with auditory features.
Fertig E et al.
Neurology, 2003
Exclusion mapping of the genetic predisposition for cervical artery dissections by linkage analysis.
Grond-Ginsbach C et al.
Annals of Neurology, 2002
LGI1 is mutated in familial temporal lobe epilepsy characterized by aphasic seizures.
Gu W et al.
Annals of Neurology, 2002