Associated Papers
Biallelic LGI1 and ADAM23 variants cause hippocampal epileptic encephalopathy via the LGI1-ADAM22/23 pathway.
Hirano Y et al.
Brain : a Journal of Neurology, 2025
A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice.
Teng XY et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2022
The LGI1 protein: molecular structure, physiological functions and disruption-related seizures.
Baudin P et al.
Cellular and Molecular Life Sciences : Cmls, 2021
Insights into the mechanisms of epilepsy from structural biology of LGI1-ADAM22.
Yamagata A et al.
Cellular and Molecular Life Sciences : Cmls, 2020
ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment.
Hivert B et al.
Journal of Cell Science, 2019
Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Yamagata A et al.
Nature Communications, 2018
Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.
Dazzo E et al.
Plos Genetics, 2016
Genetic models of focal epilepsies.
Boillot M et al.
Journal of Neuroscience Methods, 2016
Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation.
Kesim YF et al.
Epilepsy Research, 2016
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Yokoi N et al.
Nature Medicine, 2015
Evaluation of seizure foci and genes in the Lgi1(L385R/+) mutant rat.
Fumoto N et al.
Neuroscience Research, 2014
The molecular biology of genetic-based epilepsies.
Deng H et al.
Molecular Neurobiology, 2014
A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy.
Lee MK et al.
Seizure, 2014
Hyperactive behavior in a family with autosomal dominant lateral temporal lobe epilepsy caused by a mutation in the LGI1/epitempin gene.
Berghuis B et al.
Epilepsy & Behavior : E&b, 2013
A rat model for LGI1-related epilepsies.
Baulac S et al.
Human Molecular Genetics, 2012
Genetics of epilepsy and relevance to current practice.
Michelucci R et al.
Current Neurology and Neuroscience Reports, 2012
Familial temporal lobe epilepsy with psychic auras associated with a novel LGI1 mutation.
Striano P et al.
Neurology, 2011
A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.
Leonardi E et al.
Plos One, 2011