Associated Papers
Phenylbutyrate for monogenetic epilepsy: Literature review.
Stone A et al.
Epilepsy Research, 2025
Structural insights into heterohexameric assembly of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Yamaguchi T et al.
Elife, 2025
A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice.
Teng XY et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2022
The LGI1 protein: molecular structure, physiological functions and disruption-related seizures.
Baudin P et al.
Cellular and Molecular Life Sciences : Cmls, 2021
ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment.
Hivert B et al.
Journal of Cell Science, 2019
Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Yamagata A et al.
Nature Communications, 2018
Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation.
Traynelis J et al.
Genome Research, 2017
Induced pluripotent stem cells derived from an autosomal dominant lateral temporal epilepsy (ADLTE) patient carrying S473L mutation in leucine-rich glioma inactivated 1 (LGI1).
Tan GW et al.
Stem Cell Research, 2017
The LGI1-ADAM22 protein complex in synaptic transmission and synaptic disorders.
Fukata Y et al.
Neuroscience Research, 2017
Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.
Dazzo E et al.
Plos Genetics, 2016
Genetic models of focal epilepsies.
Boillot M et al.
Journal of Neuroscience Methods, 2016
Screening LGI1 in a cohort of 26 lateral temporal lobe epilepsy patients with auditory aura from Turkey detects a novel de novo mutation.
Kesim YF et al.
Epilepsy Research, 2016
Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy.
Yokoi N et al.
Nature Medicine, 2015
A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.
Leonardi E et al.
Plos One, 2011
Mutations in LGI1 gene in Japanese families with autosomal dominant lateral temporal lobe epilepsy: the first report from Asian families.
Kawamata J et al.
Epilepsia, 2010
LGI1 mutations in autosomal dominant and sporadic lateral temporal epilepsy.
Nobile C et al.
Human Mutation, 2009
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Penetrance of LGI1 mutations in autosomal dominant partial epilepsy with auditory features.
Rosanoff MJ et al.
Neurology, 2008
Genetic etiology of new forms of familial epilepsy.
Wang X et al.
Frontiers in Bioscience : a Journal and Virtual Library, 2008
Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases.
Matsushima N et al.
Cellular and Molecular Life Sciences : Cmls, 2005
LGI1: a gene involved in epileptogenesis and glioma progression?
Gu W et al.
Neurogenetics, 2005