Associated Papers
Promoted Misrejoining of X-ray Radiation-induced DNA Double-Strand Breaks in Novel DNA Ligase IV-Deficient Mouse Cells.
Kawata M et al.
Radiation Research, 2026
DNA damage and repair: underlying mechanisms leading to microcephaly.
Ribeiro JH et al.
Frontiers in Cell and Developmental Biology, 2023
Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.
Lun MP et al.
The American Journal of Pathology, 2019
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Enriquez-Rios V et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2017
Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.
Dooley J et al.
Nature Genetics, 2016
The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining.
Park J et al.
Journal of Immunology (baltimore, Md. : 1950), 2016
Congenital microcephaly.
Alcantara D et al.
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics, 2014
PRKDC mutations in a SCID patient with profound neurological abnormalities.
Woodbine L et al.
The Journal of Clinical Investigation, 2013
Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility.
Zhao P et al.
Bmc Cancer, 2013
Structure of the catalytic region of DNA ligase IV in complex with an Artemis fragment sheds light on double-strand break repair.
Ochi T et al.
Structure (london, England : 1993), 2013
Structural insights into the role of domain flexibility in human DNA ligase IV.
Ochi T et al.
Structure (london, England : 1993), 2012
Requirement for DNA ligase IV during embryonic neuronal development.
Gatz SA et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2011
[Relationship between genetic polymorphisms of DAT1 VNTR and cancer with abnormal Hilit].
Peng X et al.
Wei Sheng Yan Jiu = Journal of Hygiene Research, 2010
Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.
Rucci F et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010
Ligase IV syndrome.
Chistiakov DA
Advances in Experimental Medicine and Biology, 2010
Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.
Nijnik A et al.
The Journal of Clinical Investigation, 2009
Unravelling the association of partial T-cell immunodeficiency and immune dysregulation.
Liston A et al.
Nature Reviews. Immunology, 2008
DNA repair is limiting for haematopoietic stem cells during ageing.
Nijnik A et al.
Nature, 2007