Varaico: Literature-Extracted Genetic Variants

Gene:LIM2
Variant:p.S137S
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LIM2

NM_001161748.2:p.S137S

Associated Papers

Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation.

Robertson LK et al.

Journal of Immunology (baltimore, Md. : 1950), 2011

Roles for the tubulin- and PTP-PEST-binding paxillin LIM domains in cell adhesion and motility.

Brown MC et al.

The International Journal of Biochemistry & Cell Biology, 2002

Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.

Brown MC et al.

The Journal of Cell Biology, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."