Varaico: Literature-Extracted Genetic Variants

Gene:LIMK1
Variant:p.D460A
Back to variants list

LIMK1

NM_002314.4:p.D460A

Associated Papers

Tandem LIM domain-containing proteins, LIMK1 and LMO1, directly bind to force-bearing keratin intermediate filaments.

Kim DS et al.

Cell Reports, 2024

LIM kinase1 regulates mitotic centrosome integrity via its activity on dynein light intermediate chains.

Ou S et al.

Open Biology, 2018

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.

Jayo A et al.

Bmc Biology, 2012

The Cdk inhibitor p57(Kip2) controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics.

Vlachos P et al.

Oncogene, 2009

p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus.

Yokoo T et al.

The Journal of Biological Chemistry, 2003

Nuclear export of LIM-kinase 1, mediated by two leucine-rich nuclear-export signals within the PDZ domain.

Yang N et al.

The Biochemical Journal, 1999

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."