Varaico: Literature-Extracted Genetic Variants

Gene:LIMK1
Variant:p.T508A
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LIMK1

NM_002314.4:p.T508A

Associated Papers

Autoregulation of the LIM kinases by their PDZ domain.

Casanova-Sepúlveda G et al.

Nature Communications, 2023

38114480 (PubMed )
Supplement: 41467_2023_44148_MOESM2_ESM.pdf

A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.

Jayo A et al.

Bmc Biology, 2012

The Cdk inhibitor p57(Kip2) controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics.

Vlachos P et al.

Oncogene, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."