Varaico: Literature-Extracted Genetic Variants

Gene:LIPC
Variant:p.V84M
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LIPC

NM_000236.3:p.V84M

Associated Papers

A Comprehensive Review of the Genetics of Dyslipidemias and Risk of Atherosclerotic Cardiovascular Disease.

Kalwick M et al.

Nutrients, 2025

Effect of genetic variations in drug transporters, metabolizing enzyme and regulatory genes on the development of HIV-associated lipodystrophy.

Shyamveer et al.

The Journal of Gene Medicine, 2023

Association of SNPs in Lipid Metabolism Gene Single Nucleotide Polymorphism with the Risk of Obesity in Children.

Kulaeva ED et al.

Genetic Testing and Molecular Biomarkers, 2021

The -514C>T polymorphism in the LIPC gene modifies type 2 diabetes risk through modulation of HDL-cholesterol levels in Mexicans.

Guerra-García MT et al.

Journal of Endocrinological Investigation, 2021

Functional Haplotype of LIPC Induces Triglyceride-Mediated Suppression of HDL-C Levels According to Genome-Wide Association Studies.

Liao YH et al.

Genes, 2021

Quantile-Dependent Expressivity and Gene-Lifestyle Interactions Involving High-Density Lipoprotein Cholesterol.

Williams PT

Lifestyle Genomics, 2021

Lipase C, Hepatic Type -250A/G (rs2070895) Variant Enhances Carotid Atherosclerosis in Normolipidemic and Asymptomatic Individuals from Brazil.

Zago VHS et al.

Lipids, 2020

Hepatic lipase (LIPC) sequencing in individuals with extremely high and low high-density lipoprotein cholesterol levels.

Pirim D et al.

Plos One, 2020

Association of LIPC -250G/A and -514C/T polymorphisms and hypertension: a systematic review and meta-analysis.

Zhao X et al.

Lipids in Health and Disease, 2018

A mega-analysis of expression quantitative trait loci (eQTL) provides insight into the regulatory architecture of gene expression variation in liver.

Strunz T et al.

Scientific Reports, 2018

Association of the CETP Taq1B and LIPG Thr111Ile Polymorphisms with Glycated Hemoglobin and Blood Lipids in Newly Diagnosed Hyperlipidemic Patients.

Agapakis D et al.

Canadian Journal of Diabetes, 2016

The rs2070895 (-250G/A) Single Nucleotide Polymorphism in Hepatic Lipase (HL) Gene and the Risk of Coronary Artery Disease in North Indian Population: A Case-Control Study.

Verma P et al.

Journal of Clinical and Diagnostic Research : Jcdr, 2016

Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation.

Corsetti JP et al.

Atherosclerosis, 2016

Association between two common polymorphisms (single nucleotide polymorphism -250G/A and -514C/T) of the hepatic lipase gene and coronary artery disease in type 2 diabetic patients.

Mohammadzadeh G et al.

Advanced Biomedical Research, 2016

Variants -250G/A and -514C/T in the LIPC gene are associated with hypertensive disorders of pregnancy in Chinese women.

Lin H et al.

Genetics and Molecular Research : Gmr, 2014

Lack of association between LIPC-514 C/T polymorphism of hepatic lipase and endometriosis in Iranian women.

Sahmani M et al.

The Journal of Obstetrics and Gynaecology Research, 2014

[The association study of the LIPC -250g/A polymorphism and high-carbohydrate/low-fat diet induced serum lipid and apolipoprotein concentration changes in healthy youth].

Hu MS et al.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition, 2013

Association of LIPC and advanced age-related macular degeneration.

Lee J et al.

Eye (london, England), 2013

Genetic polymorphisms in LDLR, APOB, PCSK9 and other lipid related genes associated with familial hypercholesterolemia in Malaysia.

Lye SH et al.

Plos One, 2013

Diplotyper: diplotype-based association analysis.

Kim S et al.

Bmc Medical Genomics, 2013

Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.

Xiao Z et al.

Lipids in Health and Disease, 2012

Several genetic polymorphisms interact with overweight/obesity to influence serum lipid levels.

Yin RX et al.

Cardiovascular Diabetology, 2012

Association of several lipid-related gene polymorphisms and blood pressure variation in the Bai Ku Yao population.

Yin RX et al.

American Journal of Hypertension, 2012

Coronary heart disease diagnosis by artificial neural networks including genetic polymorphisms and clinical parameters.

Atkov OY et al.

Journal of Cardiology, 2012

Interactions of several lipid-related gene polymorphisms and cigarette smoking on blood pressure levels.

Yin RX et al.

International Journal of Biological Sciences, 2012

Several lipid-related gene polymorphisms interact with overweight/obesity to modulate blood pressure levels.

Yin RX et al.

International Journal of Molecular Sciences, 2012

Hepatic lipase gene -514C>T variant is associated with exercise training-induced changes in VLDL and HDL by lipoprotein lipase.

Brinkley TE et al.

Journal of Applied Physiology (bethesda, Md. : 1985), 2011

Vertebrate hepatic lipase genes and proteins: a review supported by bioinformatic studies.

Holmes RS et al.

Open Access Bioinformatics, 2011

Interaction between cholesteryl ester transfer protein and hepatic lipase encoding genes and the risk of type 2 diabetes: results from the Telde study.

López-Ríos L et al.

Plos One, 2011

[Influence of genetic combinations on HDL-C levels in a Southern Brazilian population].

Andrade FM et al.

Arquivos Brasileiros De Cardiologia, 2010

Genetic causes of high and low serum HDL-cholesterol.

Weissglas-Volkov D et al.

Journal of Lipid Research, 2010

Association of LIPC -250G>A polymorphism and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations.

Meng L et al.

Lipids in Health and Disease, 2010

Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.

Hodoglugil U et al.

Journal of Lipid Research, 2010

A field synopsis and meta-analysis of genetic association studies in peripheral arterial disease: The CUMAGAS-PAD database.

Zintzaras E et al.

American Journal of Epidemiology, 2009

LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.

Feitosa MF et al.

Atherosclerosis, 2009

Upstream Stimulatory Factors 1 and 2 activate the human hepatic lipase promoter via E-box dependent and independent mechanisms.

van Deursen D et al.

Biochimica Et Biophysica Acta, 2009

Lp(a) and risk of recurrent cardiac events in obese postinfarction patients.

Corsetti JP et al.

Obesity (silver Spring, Md.), 2008

High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.

van Acker BA et al.

Atherosclerosis, 2008

The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.

Grarup N et al.

The Journal of Clinical Endocrinology and Metabolism, 2008

[Association of hepatic lipase gene promoter polymorphism -514C/T with nonalcoholic fatty liver disease].

Zhan Q et al.

Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology, 2008

Plasminogen activator inhibitor-1 polymorphism (4G/5G) predicts recurrence in nonhyperlipidemic postinfarction patients.

Corsetti JP et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008

Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study.

Kilpeläinen TO et al.

Metabolism: Clinical and Experimental, 2008

Prediction of genetic risk for dyslipidemia.

Yamada Y et al.

Genomics, 2007

Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy.

Arnedo M et al.

Pharmacogenetics and Genomics, 2007

Genetic determinants of HDL: monogenic disorders and contributions to variation.

Klos KL et al.

Current Opinion in Cardiology, 2007

A Bayesian multilocus association method: allowing for higher-order interaction in association studies.

Albrechtsen A et al.

Genetics, 2007

Prediction of genetic risk for metabolic syndrome.

Yamada Y et al.

Atherosclerosis, 2007

Genetic factors affecting HDL levels, structure, metabolism and function.

Sviridov D et al.

Current Opinion in Lipidology, 2007

Upstream transcription factor 1 gene polymorphisms are associated with high antilipolytic insulin sensitivity and show gene-gene interactions.

Kantartzis K et al.

Journal of Molecular Medicine (berlin, Germany), 2007

Genetic factors for obesity.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."