Varaico: Literature-Extracted Genetic Variants

Gene:LIPC
Variant:p.S160S
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LIPC

NM_000236.3:p.S160S

Associated Papers

Effect of genetic variations in drug transporters, metabolizing enzyme and regulatory genes on the development of HIV-associated lipodystrophy.

Shyamveer et al.

The Journal of Gene Medicine, 2023

Low High-Density Lipoprotein Cholesterol and High White Blood Cell Counts: A Mendelian Randomization Study.

Harsløf M et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2021

CETP, LIPC, and SCARB1 variants in individuals with extremely high high-density lipoprotein-cholesterol levels.

Lee CJ et al.

Scientific Reports, 2019

Expression analysis of candidate genes for fatty acid composition in adipose tissue and identification of regulatory regions.

Revilla M et al.

Scientific Reports, 2018

Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Paththinige CS et al.

Lipids in Health and Disease, 2017

Elevated remnant cholesterol in 25-hydroxyvitamin D deficiency in the general population: Mendelian randomization study.

Ooi EM et al.

Circulation. Cardiovascular Genetics, 2014

Association of hepatic lipase gene polymorphisms with hypertriglyceridemia and low high-density lipoprotein-cholesterol levels among South Indian subjects without diabetes.

Ayyappa KA et al.

Diabetes Technology & Therapeutics, 2013

Gene-diet interactions on plasma lipid levels in the Inuit population.

Rudkowska I et al.

The British Journal of Nutrition, 2013

Remnant cholesterol as a causal risk factor for ischemic heart disease.

Varbo A et al.

Journal of the American College of Cardiology, 2013

Several genetic polymorphisms interact with overweight/obesity to influence serum lipid levels.

Yin RX et al.

Cardiovascular Diabetology, 2012

LCAT, HDL cholesterol and ischemic cardiovascular disease: a Mendelian randomization study of HDL cholesterol in 54,500 individuals.

Haase CL et al.

The Journal of Clinical Endocrinology and Metabolism, 2012

A Novel Mathematical Approach to Define the Genes/SNPs Conferring Risk or Protection in Sporadic Amyotrophic Lateral Sclerosis Based on Auto Contractive Map Neural Networks and Graph Theory.

Buscema M et al.

Neurology Research International, 2012

Hepatic lipase gene -514C>T variant is associated with exercise training-induced changes in VLDL and HDL by lipoprotein lipase.

Brinkley TE et al.

Journal of Applied Physiology (bethesda, Md. : 1985), 2011

Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry.

Ahmad T et al.

Circulation. Cardiovascular Genetics, 2011

Gene polymorphisms in APOE, NOS3, and LIPC genes may be risk factors for cardiac adverse events after primary CABG.

Eifert S et al.

Journal of Cardiothoracic Surgery, 2009

Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease.

Johannsen TH et al.

The Journal of Clinical Endocrinology and Metabolism, 2009

Hepatic lipase gene -514C/T polymorphism in the Guangxi Hei Yi Zhuang and Han populations.

Wu J et al.

Lipids, 2008

Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations.

Iijima H et al.

Journal of Human Genetics, 2008

Lipoprotein lipase 1595 c/g and hepatic lipase -480 c/t polymorphisms--impact on lipid profile in incident dialysis patients.

Chmielewski M et al.

Blood Purification, 2008

Genetic determinants of plasma lipoproteins.

Pollex RL et al.

Nature Clinical Practice. Cardiovascular Medicine, 2007

The C-480T hepatic lipase polymorphism is associated with HDL-C but not with risk of coronary heart disease.

McCaskie PA et al.

Clinical Genetics, 2006

Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: potential interaction with obesity.

Zhang C et al.

Diabetologia, 2006

Assessment of the role of genetic polymorphism in venous thrombosis through artificial neural networks.

Penco S et al.

Annals of Human Genetics, 2005

Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics.

Johnson AD et al.

Pharmacology & Therapeutics, 2005

Hepatic lipase genotype, diabetes risk, and implications for preventative medicine.

Shuldiner AR et al.

The Journal of Clinical Endocrinology and Metabolism, 2004

Gene interactions and stroke risk in children with sickle cell anemia.

Hoppe C et al.

Blood, 2004

Effects of the hepatic lipase gene and physical activity on coronary heart disease risk.

Hokanson JE et al.

American Journal of Epidemiology, 2003

Genetic study of common variants at the Apo E, Apo AI, Apo CIII, Apo B, lipoprotein lipase (LPL) and hepatic lipase (LIPC) genes and coronary artery disease (CAD): variation in LIPC gene associates with clinical outcomes in patients with established CAD.

Baroni MG et al.

Bmc Medical Genetics, 2003

Hepatic lipase: a marker for cardiovascular disease risk and response to therapy.

Zambon A et al.

Current Opinion in Lipidology, 2003

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.

Skoglund-Andersson C et al.

Atherosclerosis, 2003

Loci for CETP, LPL, LIPC, and APOC3 affect plasma lipoprotein size and sub-population distribution in Hispanic and non-Hispanic white subjects: the Columbia University BioMarkers Study.

Humphries SE et al.

Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd, 2002

Carotid intima-media thickness is associated with allelic variants of stromelysin-1, interleukin-6, and hepatic lipase genes: the Northern Manhattan Prospective Cohort Study.

Rundek T et al.

Stroke, 2002

Polymorphism of HL +1075C, but not -480T, is associated with plasma high density lipoprotein cholesterol and apolipoprotein AI in men of a Chinese population.

Fang DZ et al.

Atherosclerosis, 2002

A common promoter polymorphism in the hepatic lipase gene (LIPC-480C>T) is associated with an increase in coronary calcification in type 1 diabetes.

Hokanson JE et al.

Diabetes, 2002

Hepatic lipase gene -514 C/T polymorphism and premature coronary heart disease.

Ji J et al.

Journal of Cardiovascular Risk, 2002

Allele frequencies for candidate genes in atherosclerosis and diabetes among Trinidadian neonates.

Hegele RA et al.

Human Biology, 2001

Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor.

Botma GJ et al.

Atherosclerosis, 2001

Absence of association between genetic variation in the LIPC gene promoter and plasma lipoproteins in three Canadian populations.

Hegele RA et al.

Atherosclerosis, 1999

Hepatic lipase gene polymorphisms influence plasma HDL levels. Results from Finnish EARS participants. European Atherosclerosis Research Study.

Murtomäki S et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."