Associated Papers
Steroid hormone receptors, exome sequencing and treatment responsiveness of breast cancer patient-derived xenografts originated in a South American country.
Pataccini G et al.
Scientific Reports, 2025
Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease.
Petrazzini BO et al.
Nature Genetics, 2024
Advances in Dyslipidaemia Treatments: Focusing on ApoC3 and ANGPTL3 Inhibitors.
Tomlinson B et al.
Journal of Lipid and Atherosclerosis, 2024
Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene.
Fierheller CT et al.
Genes, 2023
Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants.
Young KL et al.
Hgg Advances, 2023
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4.
Landfors F et al.
Journal of Lipid Research, 2023
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.
Mishra A et al.
Brain : a Journal of Neurology, 2022
Sphingosine-1-phosphate: metabolism, transport, atheroprotection and effect of statin treatment.
Therond P et al.
Current Opinion in Lipidology, 2022
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.
Sarnowski C et al.
Communications Biology, 2022
Genetic Determinants of Plasma Low-Density Lipoprotein Cholesterol Levels: Monogenicity, Polygenicity, and "Missing" Heritability.
Martín-Campos JM
Biomedicines, 2021
Analysis of 200 000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.
Curtis D
Psychiatric Genetics, 2021
The genetic basis of major depression.
Kendall KM et al.
Psychological Medicine, 2021
Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins.
Khetarpal SA et al.
Plos Genetics, 2021
Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance.
Adam RC et al.
Journal of Lipid Research, 2020
Sex differences in the genetic architecture of depression.
Kang HJ et al.
Scientific Reports, 2020
Missing heritability in Parkinson's disease: the emerging role of non-coding genetic variation.
Ohnmacht J et al.
Journal of Neural Transmission (vienna, Austria : 1996), 2020
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.
Mishra A et al.
Brain : a Journal of Neurology, 2019
[Breakthrough in understanding the molecular causes of psychiatric disorders].
Nöthen MM et al.
Der Nervenarzt, 2019
Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans.
Khetarpal SA et al.
Circulation. Genomic and Precision Medicine, 2018
HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology.
Rosenson RS et al.
Nature Reviews. Cardiology, 2018
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.
Lu X et al.
Nature Genetics, 2017
HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics.
Vitali C et al.
Current Cardiology Reports, 2017
Polygenic determinants in extremes of high-density lipoprotein cholesterol.
Dron JS et al.
Journal of Lipid Research, 2017
Progress in Genetic Studies of Tourette's Syndrome.
Qi Y et al.
Brain Sciences, 2017
A decade of progress on the genetic basis of coronary artery disease. Practical insights for the internist.
Girelli D et al.
European Journal of Internal Medicine, 2017
Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms.
Amin N et al.
Molecular Psychiatry, 2017
Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms.
Amin N et al.
Molecular Psychiatry, 2017
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.
Dewey FE et al.
Science (new York, N.y.), 2016
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease.
Helgadottir A et al.
Nature Genetics, 2016
Insights into blood lipids from rare variant discovery.
Schmidt EM et al.
Current Opinion in Genetics & Development, 2015
PLTP activity inversely correlates with CAAD: effects of PON1 enzyme activity and genetic variants on PLTP activity.
Kim DS et al.
Journal of Lipid Research, 2015
Human genetics of HDL: Insight into particle metabolism and function.
Brunham LR et al.
Progress in Lipid Research, 2015
Unraveling new therapeutic targets of coronary artery disease by genetic approaches.
Lee SE et al.
Circulation Journal : Official Journal of the Japanese Circulation Society, 2015
XomAnnotate: Analysis of Heterogeneous and Complex Exome- A Step towards Translational Medicine.
Talukder AK et al.
Plos One, 2015
Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients.
Arndt C et al.
Diabetes & Metabolism, 2014
Association of cholesteryl ester transfer protein (CETP) gene polymorphism, high density lipoprotein cholesterol and risk of coronary artery disease: a meta-analysis using a Mendelian randomization approach.
Wu Z et al.
Bmc Medical Genetics, 2014
Mendelian randomization studies in coronary artery disease.
Jansen H et al.
European Heart Journal, 2014
Identification of four novel genes contributing to familial elevated plasma HDL cholesterol in humans.
Singaraja RR et al.
Journal of Lipid Research, 2014
LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias.
Johansen CT et al.
Journal of Lipid Research, 2014
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.
Holmen OL et al.
Nature Genetics, 2014
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Peloso GM et al.
American Journal of Human Genetics, 2014
Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics.
Larach DB et al.
Clinical Lipidology, 2013
Genetics of lipid traits and relationship to coronary artery disease.
Keenan TE et al.
Current Cardiology Reports, 2013
Validating therapeutic targets through human genetics.
Plenge RM et al.
Nature Reviews. Drug Discovery, 2013
The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans.
Singaraja RR et al.
Circulation. Cardiovascular Genetics, 2013