Associated Papers
Deletion of the Lmna gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretory phenotype.
Rouhi L et al.
The Journal of Cardiovascular Aging, 2022
Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy.
Rouhi L et al.
Cardiovascular Research, 2021
Clinical Interpretation and Management of Genetic Variants.
Marian AJ
Jacc. Basic to Translational Science, 2020
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C-deficient mice.
Auguste G et al.
The Journal of Clinical Investigation, 2020
Genetic basis and molecular biology of cardiac arrhythmias in cardiomyopathies.
Marian AJ et al.
Cardiovascular Research, 2020
Non-syndromic cardiac progeria in a patient with the rare pathogenic p.Asp300Asn variant in the LMNA gene.
Marian AJ
Bmc Medical Genetics, 2017
The enigma of genetics etiology of atherosclerosis in the post-GWAS era.
Marian AJ
Current Atherosclerosis Reports, 2012
Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy.
Rodriguez G et al.
Circulation. Cardiovascular Genetics, 2011
Strategic approaches to unraveling genetic causes of cardiovascular diseases.
Marian AJ et al.
Circulation Research, 2011
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