Varaico: Literature-Extracted Genetic Variants

Gene:LOX
Variant:p.R158Q
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LOX

NM_002317.7:p.R158Q

Associated Papers

Single Nucleotide Polymorphisms as Markers of Genetic Susceptibility for Oral Submucous Fibrosis Risk: A Systematic Review and Meta-Analysis.

Gopinath D et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2026

Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis.

Cai J et al.

Signal Transduction and Targeted Therapy, 2024

39307879 (PubMed )
Supplement: 41392_2024_1960_MOESM6_ESM.xlsx › Table_S5

Serum and salivary Cu/Zn ratio as a diagnostic biomarker for oral submucosal fibrosis: an analysis of trace metals and LOX gene variants.

Shah R et al.

Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, 2024

Association of LOX gene G473A polymorphism with the occurrence of allergic rhinitis and efficacy of montelukast sodium in children.

Yao X et al.

Cell Cycle (georgetown, Tex.), 2023

The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.

Peymanfar Y et al.

International Journal of Molecular Sciences, 2023

Genomic characterization of lymphomas in patients with inborn errors of immunity.

Ye X et al.

Blood Advances, 2022

35687490 (PubMed )
Supplement: advancesADV2021006654-suppl4.xlsx › PL23

The Genetic Architecture of Non-Syndromic Rhegmatogenous Retinal Detachment.

Moledina M et al.

Genes, 2022

Serum Lysyl Oxidase Levels and Lysyl Oxidase Gene Polymorphism in Ovarian Cancer Patients of Eastern Indian Population.

Kumari S et al.

Diagnostics (basel, Switzerland), 2021

Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy.

Schmitt M et al.

Cancers, 2021

34771574 (PubMed )
Supplement: cancers-13-05411-s001.zip › cancers-1421686_Table_S4.xlsx › Sheet_1

Induction of osteoclast formation by LOX mutant (LOXG473A) through regulation of autophagy.

Zhang B et al.

Annals of Translational Medicine, 2021

Effect of Lysyl Oxidase G473 A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis.

Mukherjee S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2021

Genetic polymorphism of lysyl oxidase, glutathione S-transferase M1, glutathione-S-transferase T1, and glutathione S-transferase P1 genes as risk factors for lung cancer in Egyptian patients.

El-Deek SEM et al.

Molecular Biology Reports, 2021

Polymorphisms in Lysyl Oxidase Family Genes Are Associated With Intracranial Aneurysm Susceptibility in a Chinese Population.

Luo C et al.

Frontiers in Endocrinology, 2021

Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer.

Lin HY et al.

International Journal of Molecular Sciences, 2020

A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer.

de la Cueva A et al.

Carcinogenesis, 2018

Elevated Aromatase (CYP19A1) Expression Is Associated with a Poor Survival of Patients with Estrogen Receptor Positive Breast Cancer.

Friesenhengst A et al.

Hormones & Cancer, 2018

Functional importance of lysyl oxidase family propeptide regions.

Trackman PC

Journal of Cell Communication and Signaling, 2018

Impact of lysyl oxidase (G473A) polymorphism on diabetic foot ulcers.

Pichu S et al.

International Journal of Biological Macromolecules, 2017

A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans.

Hong EP et al.

Yonsei Medical Journal, 2017

Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer.

Fraga A et al.

Bmc Urology, 2017

Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.

Wang G et al.

International Journal of Environmental Research and Public Health, 2016

LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections.

Guo DC et al.

Circulation Research, 2016

Association of GRM4 gene polymorphisms with susceptibility and clinicopathological characteristics of osteosarcoma in Guangxi Chinese population.

Wang K et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

Lysyl oxidase rs1800449 polymorphism and cancer risk among Asians: evidence from a meta-analysis and a case-control study of colorectal cancer.

Gao X et al.

Molecular Genetics and Genomics : Mgg, 2015

Association of Lysyl oxidase (LOX) Polymorphisms with the Risk of Keratoconus in an Iranian Population.

Hasanian-Langroudi F et al.

Ophthalmic Genetics, 2015

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A8-A0A4-01A.domain

Lysyl oxidase genetic variants affect gene expression in cervical cancer.

Bu M et al.

Dna and Cell Biology, 2014

Molecular screening of lysyl oxidase G473A polymorphism in oral submucous fibrosis.

Thorawat A et al.

Journal of Oral and Maxillofacial Pathology : Jomfp, 2014

Lysyl oxidase genetic variants and the prognosis of glioma.

Han S et al.

Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica, 2014

XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis.

Yan Y et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

COL1A1 polymorphism is associated with risks of osteosarcoma susceptibility and death.

He M et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Fibroblast growth factor receptor 4 polymorphisms and the prognosis of non-Hodgkin lymphoma.

Cha Z et al.

Molecular Biology Reports, 2014

Association of ITGA3 gene polymorphisms with susceptibility and clinicopathological characteristics of osteosarcoma.

Yang W et al.

Medical Oncology (northwood, London, England), 2014

Association of the G473A polymorphism and expression of lysyl oxidase with breast cancer risk and survival in European women: a hospital-based case-control study.

Friesenhengst A et al.

Plos One, 2014

Lack of association of lysyl oxidase (LOX) gene polymorphisms with intracranial aneurysm in a south Indian population.

Sathyan S et al.

Molecular Biology Reports, 2013

Comparative distribution of Lysyl Oxidase (G473A) and NQO1 (C609T) polymorphism among tea-garden workers (habitual chewers of betel quid) of Darjeeling district and Kolkata city of West Bengal.

Ray JG et al.

Contemporary Clinical Dentistry, 2013

Effects of lysyl oxidase genetic variants on the susceptibility to rhegmatogenous retinal detachment and proliferative vitreoretinopathy.

Yu H et al.

Inflammation, 2013

mEH Tyr113His polymorphism and the risk of ovarian cancer development.

Zhong JH et al.

Journal of Ovarian Research, 2013

Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide.

Sato S et al.

Plos One, 2013

The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer.

Shi W et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2012

Lysyl oxidase polymorphisms and ischemic stroke--a case control study.

Zhang HF et al.

Molecular Biology Reports, 2012

Fibroblast growth factor receptor 4 polymorphisms and coronary artery disease: a case control study.

Zhu Q et al.

Molecular Biology Reports, 2012

Lysyl oxidase G473A polymorphism is associated with increased risk of ovarian cancer.

Wu J et al.

Genetic Testing and Molecular Biomarkers, 2012

Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies.

Bykhovskaya Y et al.

Investigative Ophthalmology & Visual Science, 2012

Association between lysyl oxidase G473A polymorphism and ovarian cancer in the Han Chinese population.

Wang X et al.

The Journal of International Medical Research, 2012

Lysyl oxidase polymorphisms and susceptibility to osteosarcoma.

Liu Y et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."