Varaico: Literature-Extracted Genetic Variants

Gene:LRP1
Variant:p.L9V
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LRP1

NM_002332.3:p.L9V

Associated Papers

Genetic determinants of activated factor VII-antithrombin plasma levels and mortality in patients with coronary artery disease.

Osti N et al.

Thrombosis Research, 2025

A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels.

Lee JD et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2017

Genetic variations in sites of affinity between FVIII and LRP1 are not associated with high FVIII levels in venous thromboembolism.

Bittar LF et al.

Scientific Reports, 2015

Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile.

Martinelli N et al.

Blood, 2010

LDL receptor polymorphisms revisited.

Bovenschen N

Blood, 2010

Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.

Vormittag R et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

Contribution of low density lipoprotein receptor-related protein genotypes to coagulation factor VIII levels in thrombotic women.

Marchetti G et al.

Haematologica, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."