Varaico: Literature-Extracted Genetic Variants

Gene:LRP1
Variant:p.T221T
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LRP1

NM_002332.3:p.T221T

Associated Papers

LRP1 and APOA1 Polymorphisms: Impact on Warfarin International Normalized Ratio-Related Phenotypes.

Li D et al.

Journal of Cardiovascular Pharmacology, 2020

Thrombophilia, risk factors and prevention.

Campello E et al.

Expert Review of Hematology, 2019

Genetic regulation of plasma von Willebrand factor levels in health and disease.

Swystun LL et al.

Journal of Thrombosis and Haemostasis : Jth, 2018

A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels.

Lee JD et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2017

Genetic variations in sites of affinity between FVIII and LRP1 are not associated with high FVIII levels in venous thromboembolism.

Bittar LF et al.

Scientific Reports, 2015

Inherited Thrombophilia.

Phillippe HM et al.

Journal of Pharmacy Practice, 2014

LRP1/CD91 is up-regulated in monocytes from patients with haemophilia A: a single-centre analysis.

Franchini M et al.

Haemophilia : the Official Journal of the World Federation of Hemophilia, 2013

Elevated factor VIII levels and risk of venous thrombosis.

Jenkins PV et al.

British Journal of Haematology, 2012

Thrombin generation in chronic obstructive pulmonary disease: dependence on plasma factor composition.

Undas A et al.

Thrombosis Research, 2011

Lack of association of common polymorphism of LRP1 gene with myocardial infarction in a Chinese Han population.

Ren H et al.

Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban, 2011

Coagulation factor VIII levels are associated with long-term survival - interactions with gender in a large hospital-based cohort.

Kovar FM et al.

Wiener Klinische Wochenschrift, 2010

Clearance mechanisms of von Willebrand factor and factor VIII.

Lenting PJ et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

Low-density lipoprotein receptor-related protein 1 polymorphism 663 C > T affects clotting factor VIII activity and increases the risk of venous thromboembolism.

Vormittag R et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."